Real-time monitoring of etoposide prodrug activated by hydrogen peroxide with improved safety-Reference-Cited by-同舟云学术

Real-time monitoring of etoposide prodrug activated by hydrogen peroxide with improved safety

Published:2019 Issue:47 Volume:7 Page:7548-7557
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhu Jiawen¹²³⁴,Chen Jingting¹²³⁴,Song Dongmei¹²³⁴,Zhang Wenda¹²³⁴,Guo Jianpeng¹²³⁴,Cai Guiping¹²³⁴,Ren Yuhao¹²³⁴,Wan Chengying¹²³⁴,Kong Lingyi¹²³⁴^ORCID,Yu Wenying¹²³⁴^ORCID

Affiliation:

1. Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines

2. China Pharmaceutical University

3. Nanjing 210009

4. People's Republic of China

Abstract

A novel H₂O₂ sensitive prodrug designed for selectively releasing etoposide in cancer cells with fluorescence monitoring and improved safety.

Funder

National Natural Science Foundation of China

Natural Science Research of Jiangsu Higher Education Institutions of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TB/C9TB02041A

Reference40 articles.

1. Drug Delivery Systems: Entering the Mainstream

2. Targeted drug conjugates: principles and progress

3. Recent Advances in the Chemistry and Biology of Podophyllotoxins

4. Etoposide: four decades of development of a topoisomerase II inhibitor

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