Bioinformatics for the synthetic biology of natural products: integrating across the Design–Build

Bioinformatics for the synthetic biology of natural products: integrating across the Design–Build–Test cycle

Published:2016 Issue:8 Volume:33 Page:925-932
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Carbonell Pablo¹²³⁴⁵^ORCID,Currin Andrew¹²³⁴⁵,Jervis Adrian J.¹²³⁴⁵,Rattray Nicholas J. W.¹²³⁴⁵,Swainston Neil¹²³⁴⁵,Yan Cunyu¹²³⁴⁵,Takano Eriko¹²³⁴⁵,Breitling Rainer¹²³⁴⁵

Affiliation:

1. Manchester Centre for Fine and Specialty Chemicals (SYNBIOCHEM)

2. Manchester Institute of Biotechnology

3. University of Manchester

4. Manchester M1 7DN

5. UK

Abstract

Bioinformatics tools facilitate and accelerate all steps along the Design–Build–Test cycle of synthetic biology, for the enhanced production of natural products in engineered microbes.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NP/C6NP00018E

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3. The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to Find Candidate Genes for Orphan Enzymes