Transition-metal free, radical oxidation of 1,6-enyne cyclopropanation: synthesis of aza-bicyclo[4.1.0]heptane derivatives

Author:

Meena Shivam A.1,Thakur Deepika1,Nandy Abhijit2,Ranjan Rahul3,Rai Anubhav4,Banerjee Shibdas2,Verma Akhilesh K.15ORCID

Affiliation:

1. Department of Chemistry, University of Delhi, Delhi-110007, India

2. Department of Chemistry, IISER Tirupati, Tirupati -517507, India

3. Department of Chemistry, NSUT Delhi, Delhi-110078, India

4. Department of Chemistry, IIT(ISM), Dhanbad, Jharkhand 826004, India

5. Institution of Eminence (IoE), University of Delhi, Delhi-110007, India

Abstract

A straightforward transition-metal-free sustainable methodology for oxidative cyclopropanation of aza-1,6-enynes has been devised, enabling the synthesis of valuable, functionalized azabicyclo[4.1.0]heptane-2,4,5-triones.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

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