New ruthenium(<scp>ii</scp>) complexes with cyclic thio- and semicarbazone: evaluation of cytotoxicity and effects on cell migration and apoptosis of lung cancer cells-Reference-Cited by-同舟云学术

New ruthenium(ii) complexes with cyclic thio- and semicarbazone: evaluation of cytotoxicity and effects on cell migration and apoptosis of lung cancer cells

Published:2023 Issue:28 Volume:52 Page:9590-9606
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Gonçalves Yasmim G.¹²^ORCID,Becceneri Amanda B.²,Graminha Angelica E.²³,Miranda Victor M.⁴,Rios Rafaella R.²^ORCID,Rinaldi-Neto Francisco²,Costa Mônica S.⁵,Gonçalves Ana C. R.⁶,Deflon Victor M.²,Yoneyama Kelly A. G.⁵,Maia Pedro I. S.⁶,Franca Eduardo F.⁷^ORCID,Cominetti Márcia R.³^ORCID,Silva Roberto S.²^ORCID,Von Poelhsitz Gustavo¹^ORCID

Affiliation:

1. Chemistry Institute, Federal University of Uberlândia, Uberlândia, MG, Brazil

2. Laboratório de Fotoquímica e Química Bioinorgânica, School of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, SP, Brazil

3. Gerontology Department, Federal University of São Carlos, São Carlos, SP, Brazil

4. Grupo de Química Inorgânica Estrutural e Biológica, Chemistry Institute of São Carlos, Universidade de São Paulo, USP – São Carlos, São Carlos, SP, Brazil

5. Genetic and Biochemistry Institute, Federal University of Uberlândia, Uberlândia, MG, Brazil

6. Exacts, Natural Sciences, and Education Institute, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil

7. Laboratório de Cristalografia e Química Computacional, Chemistry Institute, Federal University of Uberlândia, Uberlândia, MG, Brazil

Abstract

New ruthenium(ii) complex with phosphine and cyclic thio- and semicarbazone classes of ligands presents a high selectivity index, anti-migration properties and induces apoptosis cell death mechanism against lung cancer cells.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00750B

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