Laser-synthesized plasmonic HfN-based nanoparticles as a novel multifunctional agent for photothermal therapy

Author:

Pastukhov A. I.1,Savinov M. S.2,Zelepukin I. V.34,Babkova J. S.3ORCID,Tikhonowski G. V.2,Popov A. A.2,Klimentov S. M.2,Devi A.5,Patra A.5,Zavestovskaya I. N.267,Deyev S. M.237,Kabashin A. V.12ORCID

Affiliation:

1. Aix-Marseille University, CNRS, LP3, 13288, Marseille, France

2. MEPhI, Institute of Engineering Physics for Biomedicine (PhysBio), 115409, Moscow, Russia

3. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences, 117997, Moscow, Russia

4. Uppsala University, Department of Medicinal Chemistry, 75310, Uppsala, Sweden

5. Institute of Nano Science and Technology, Mohali, 140306, India

6. P. N. Lebedev Physical Institute of the Russian Academy of Sciences, 119991, Moscow, Russia

7. National Research Center “Kurchatov Institute”, 123182, Moscow, Russia

Abstract

HfN nanoparticles exhibiting a tunable plasmonic feature in the near-IR were synthesized by laser ablation in liquids. A strong photothermal therapeutic effect yielding 100% cells death under 808 nm irradiation of nanoparticles was reported.

Funder

Aix-Marseille Université

Agence Nationale de la Recherche

Ministry of Education and Science of the Russian Federation

Publisher

Royal Society of Chemistry (RSC)

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