Identification and inhibitory activity against α-thrombin of a novel anticoagulant peptide derived from oyster (Crassostrea gigas) protein-Reference-Cited by-同舟云学术

Identification and inhibitory activity against α-thrombin of a novel anticoagulant peptide derived from oyster (Crassostrea gigas) protein

Published:2018 Issue:12 Volume:9 Page:6391-6400
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Cheng Shuzhen¹²³⁴⁵,Tu Maolin⁶⁷⁸⁹⁵,Chen Hui⁶¹⁰¹¹¹²⁵,Xu Zhe⁶¹⁰¹¹¹²⁵,Wang Ziye⁶¹⁰¹¹¹²⁵,Liu Hanxiong⁶¹⁰¹¹¹²⁵,Zhao Guanghua²³¹³⁵^ORCID,Zhu Beiwei¹²³⁴⁵,Du Ming⁶¹⁰¹¹¹²⁵^ORCID

Affiliation:

1. Beijing Advanced Innovation Center for Food Nutrition and Human Health

2. College of Food Science and Nutritional Engineering

3. China Agricultural University

4. Beijing 100083

5. China

6. Department of Food Science and Engineering

7. School of Chemistry and Chemical Engineering

8. Harbin Institute of Technology

9. Harbin 150001

10. National Engineering Research Center of Seafood

11. Dalian Polytechnic University

12. Dalian

13. Beijing

Abstract

A newly discovered anticoagulant peptide was isolated, purified and identified from the pepsin hydrolysate of oyster (Crassostrea gigas) which could potently prolong the activated partial thromboplastin time and the thrombin time.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO01635F

Reference51 articles.

1. Stability assessment of a new antithrombotic small peptide, Arg-Gly-Asp-Trp-Arg (RGDWR), and its derivative

2. Angiotensin-converting enzyme-inhibitory and antithrombotic activities of soluble peptide extracts from buffalo and cow milk Cheddar cheeses

3. Anticoagulant activities of goby muscle protein hydrolysates