Magainin 2-derived stapled peptides derived with the ability to deliver pDNA, mRNA, and siRNA into cells-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Magainin 2-derived stapled peptides derived with the ability to deliver pDNA, mRNA, and siRNA into cells

Published:2023 Issue:38 Volume:14 Page:10403-10410
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Hirano Motoharu¹²,Yokoo Hidetomo¹³^ORCID,Goto Chihiro¹²,Oba Makoto³^ORCID,Misawa Takashi¹^ORCID,Demizu Yosuke¹²⁴^ORCID

Affiliation:

1. Division of Organic Chemistry, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki, Kanagawa 210-9501, Japan

2. Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Yokohama, Kanagawa, 230-0045, Japan

3. Medical Chemistry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 606-0823, Japan

4. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Division of Pharmaceutical Science of Okayama University, 1-1-1 Tsushimanaka, Kita 700-8530, Japan

Abstract

We have developed cell-penetrating stapled peptides based on the amphipathic antimicrobial peptide magainin 2 for intracellular delivery of nucleic acids such as pDNA, mRNA, and siRNA.

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC04124G

Reference41 articles.

1. The chemical evolution of oligonucleotide therapies of clinical utility

2. mRNA-based therapeutics — developing a new class of drugs

3. Lipid nanoparticles for mRNA delivery

4. Cellular uptake of the tat protein from human immunodeficiency virus

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP