Synthesis, X-ray crystal structure, DNA/protein binding and DNA cleavage studies of novel copper(ii) complexes of N-substituted isatin thiosemicarbazone ligands-Reference-Cited by-同舟云学术

Synthesis, X-ray crystal structure, DNA/protein binding and DNA cleavage studies of novel copper(ii) complexes of N-substituted isatin thiosemicarbazone ligands

Published:2016 Issue:3 Volume:40 Page:2661-2679
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Muralisankar Mathiyan¹²³⁴,Bhuvanesh Nattamai S. P.¹⁵⁶,Sreekanth Anandaram¹²³⁴

Affiliation:

1. Department of Chemistry

2. National Institute of Technology

3. Tiruchirappalli-620 015

4. India

5. Texas A&M University

6. USA

Abstract

Copper(ii) complexes containing isatin thiosemicarbozone ligands have been synthesized and evaluated for its biological applications like DNA/protein binding and DNA cleavage studies.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NJ/C5NJ02806J

Reference68 articles.

1. Platinum Compounds: a New Class of Potent Antitumour Agents

2. Chemical Nuclease Activity of 1,10-Phenanthroline−Copper. Isotopic Probes of Mechanism

3. Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1

4. A novel water soluble ligand bridged cobalt(ii) coordination polymer of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA binding, protein interaction, radical scavenging and anticancer activity

5. Study on potential antitumor mechanism of a novel Schiff Base copper(II) complex: Synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity

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