Single-molecule brightness analysis for the determination of anticancer drug interactions with DNA-Reference-Cited by-同舟云学术

Single-molecule brightness analysis for the determination of anticancer drug interactions with DNA

Published:2020 Issue:20 Volume:145 Page:6600-6606
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Zhou Ying¹²³⁴^ORCID,Bielec Krzysztof¹²³⁴^ORCID,Pasitsuparoad Pakorn¹²³⁴^ORCID,Hołyst Robert¹²³⁴^ORCID

Affiliation:

1. Institute of Physical Chemistry

2. Polish Academy of Sciences

3. 01-224 Warsaw

4. Poland

Abstract

We performed brightness analysis at a single molecular level of doxorubicin, daunorubicin, epirubicin, and idarubicin. The method was sensitive enough to confirm that the binding of drugs to the DNA occurs in two reactions.

Funder

Narodowe Centrum Nauki

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AN/D0AN01108H

Reference26 articles.

1. WHO , Mental and Holistic Health: Some International Perspectives , 2019 , 119–134

2. Investigations into the DNA-binding mode of doxorubicinone

3. New Insights into the Mechanism of the DNA/Doxorubicin Interaction

4. Interaction of Doxorubicin with Polynucleotides. A Spectroscopic Study

5. Unravelling molecular mechanisms in the fluorescence spectra of doxorubicin in aqueous solution by femtosecond fluorescence spectroscopy

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