Asymmetric synthesis of 1,2-fluorohydrin: iridium catalyzed hydrogenation of fluorinated allylic alcohol-Reference-Cited by-同舟云学术

Asymmetric synthesis of 1,2-fluorohydrin: iridium catalyzed hydrogenation of fluorinated allylic alcohol

Published:2020 Issue:41 Volume:11 Page:11189-11194
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ponra Sudipta¹²³⁴,Yang Jianping¹²³⁴^ORCID,Wu Haibo¹²³⁴^ORCID,Rabten Wangchuk¹²³⁴,Andersson Pher G.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Organic Chemistry

2. Stockholm University

3. SE-10691 Stockholm

4. Sweden

5. School of Chemistry and Physics

Abstract

We have developed a simple protocol for the preparation of 1,2-fluorohydrin by asymmetric hydrogenation of fluorinated allylic alcohols using an efficient azabicyclo thiazole-phosphine iridium complex.

Funder

Vetenskapsrådet

Stiftelsen Olle Engkvist Byggmästare

Knut och Alice Wallenbergs Stiftelse

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC04032K

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