Label-free counting of affinity-enriched circulating tumor cells (CTCs) using a thermoplastic micro-Coulter counter (μCC)
Author:
Affiliation:
1. Department of Chemistry
2. The University of Kansas
3. Lawrence
4. USA
5. Center of BioModular Multiscale Systems for Precision Medicine
6. BioFluidica
7. Inc.
Abstract
A micro-Coulter Counter (μCC) with simple and low cost fabrication process was developed and integrated with a circulating tumor cell (CTC) selection chip, providing label-free cell counting for CTC analysis.
Funder
National Institute of Biomedical Imaging and Bioengineering
National Cancer Institute
China Scholarship Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/AN/C9AN01802F
Reference47 articles.
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2. Microsystems for the Capture of Low-Abundance Cells
3. Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule
4. Microfluidic Sensor for Noncontact Detection of Cell Flow in a Microchannel
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