Bovine plasma hydrolysates’ iron chelating capacity and its potentiating effect on ferritin synthesis in Caco-2 cells

Author:

Gómez-Grimaldos Nathalia A.12345ORCID,Gómez-Sampedro Leidy J.12345ORCID,Zapata-Montoya José E.12345,López-García Gabriel678910,Cilla Antonio678910ORCID,Alegría-Torán Amparo678910

Affiliation:

1. Nutrition and Food Technology Group

2. Faculty of Pharmaceutical and Food Sciences

3. University of Antioquia

4. Medellin

5. Colombia

6. Nutrition and Food Science Area

7. Faculty of Pharmacy

8. University of Valencia

9. Burjassot

10. Spain

Abstract

Bovine plasma hydrolysates with a degree of hydrolysis of 19.1% have an iron chelating capacity of 38.5 ± 0.4% and increase the synthesis of ferritin in Caco-2 cells five-fold compared to the control.

Funder

Universitat de València

Universidad de Antioquia

Departamento Administrativo de Ciencia, Tecnología e Innovación (Departamento Administrativo de Ciencia, Tecnología e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Reference27 articles.

1. Food and Agriculture Organization of the United Nations (FAO), Discussion paper on biofortification with essential nutrients, Codex Alimentarius Commission development in Joint FAO/WHO food standards programme codex committee on nutrition and foods for special dietary uses 36th session, 2014, Kuta Bali-Indonesia, http://www.fao.org/tempref/codex/Meetings/CCNFSDU/ccnfsdu36/nf36_04e.pdf

2. Optimization of the Red Tilapia (Oreochromis spp.) Viscera Hydrolysis for Obtaining Iron-Binding Peptides and Evaluation of In Vitro Iron Bioavailability

3. Iron-binding peptides from whey protein hydrolysates: Evaluation, isolation and sequencing by LC–MS/MS

4. Serum albumin forms a lactoferrin-like soluble iron-binding complex in presence of hydrogen carbonate ions

5. Iron bioavailability in iron-fortified cereal foods: The contribution of in vitro studies

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