Unveiling the anti-cancer mechanism for half-sandwich and cyclometalated Ir(iii)-based complexes with functionalized α-lipoic acid-Reference-Cited by-同舟云学术

Unveiling the anti-cancer mechanism for half-sandwich and cyclometalated Ir(iii)-based complexes with functionalized α-lipoic acid

Published:2020 Issue:9 Volume:10 Page:5392-5398
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Meng-Meng¹²³⁴⁵,Xue Xu-Ling¹²³⁴⁵,Sheng Xi-Xi¹²³⁴⁵,Su Yan¹²³⁴⁵,Kong Ya-Qiong¹²³⁴⁵,Qian Yong¹²³⁴⁵,Bao Jian-Chun¹²³⁴⁵^ORCID,Su Zhi¹²³⁴⁵^ORCID,Liu Hong-Ke¹²³⁴⁵^ORCID

Affiliation:

1. Jiangsu Collaborative Innovation Center of Biomedical Functional Materials

2. College of Chemistry and Materials Science

3. Nanjing Normal University

4. Nanjing

5. China

Abstract

The introduction of LA improved the anticancer activity of the complex and helped overcome the cisplatin-resistance.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA10357K

Reference45 articles.

1. Synthesis and anticancer evaluation of α-lipoic acid derivatives

2. Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo

3. Lipoic acid – biological activity and therapeutic potential

4. α-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin β1/β3 downregulation

5. Effects of α-lipoic acid on cell proliferation and apoptosis in MDA-MB-231 human breast cells

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