Sustainable methine sources for the synthesis of heterocycles under metal- and peroxide-free conditions
Author:
Affiliation:
1. Department of Medicinal and Applied Chemistry
2. Kaohsiung Medical University
3. Kaohsiung City
4. Taiwan
5. Department of Medical Research
Abstract
Alcohols and ethers were identified as sustainable methine sources for synthesizing quinazolinone and benzimidazole derivatives using a combination of TsOH·H2O/O2 and appropriate bis-nucleophiles for the first time.
Funder
Ministry of Science and Technology, Taiwan
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/GC/C8GC03839B
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