Dual active pyrimidine-based carbocyclic nucleoside derivatives: synthesis, and <i>in silico</i> and <i>in vitro</i> anti-diabetic and anti-microbial studies-Reference-Cited by-同舟云学术

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Dual active pyrimidine-based carbocyclic nucleoside derivatives: synthesis, and in silico and in vitro anti-diabetic and anti-microbial studies

Published:2024 Issue:14 Volume:14 Page:9559-9569
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mallidi Kalyani¹,Gundla Rambabu¹,Makam Parameshwar²,Katari Naresh Kumar¹³^ORCID,Jonnalagadda Sreekantha Babu³^ORCID

Affiliation:

1. Department of Chemistry, GITAM School of Science, GITAM Deemed to be University, Hyderabad, Telangana 502329, India

2. Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University, Arcadia Grant, P.O. Chandanwari, Premnagar, Dehradun, Uttarakhand 248007, India

3. School of Chemistry & Physics, College of Agriculture, Engineering & Science, WestvilleCampus, University of KwaZulu-Natal, P Bag X 54001, Durban 4000, South Africa

Abstract

New pyrimidine-based carbocylic nucleoside derivatives with C-4 substitution for inhibiting α-glucosidase as a means of alleviating the effects of diabetes mellitus (DM) and microbial infections.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA00304G

Reference53 articles.

1. Diabetes: a dynamic disease

2. Diabetes mellitus: From molecular mechanism to pathophysiology and pharmacology

3. Treatment of type 2 diabetes: future approaches

4. Type 1 diabetes

5. Diagnosis and treatment of type 1 diabetes at the dawn of the personalized medicine era

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