Synthesis of N-arylsulfonamides via Fe-promoted reaction of sulfonyl halides with nitroarenes in an aqueous medium-Reference-Cited by-同舟云学术

Synthesis of N-arylsulfonamides via Fe-promoted reaction of sulfonyl halides with nitroarenes in an aqueous medium

Published:2018 Issue:27 Volume:16 Page:5016-5020
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Jiang Jun¹²³⁴⁵,Zeng Sheng¹²³⁴⁵,Chen De¹²³⁴⁵,Cheng Chaozhihui¹²³⁴⁵,Deng Wei¹²³⁴⁵,Xiang Jiannan¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. Hunan University

4. Changsha

5. P.R. China

Abstract

A fascinating Fe-promoted protocol for the synthesis of N-arylsulfonamides has been developed. Starting from commercially available nitroarenes and sulfonyl chlorides, moderate to excellent yields of the corresponding N-arylsulfonamides can be obtained. In particular, Fe dust was the sole reductant in the transformation and it can be easily performed on a large scale.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01172A

Reference34 articles.

1. Discovery of Novel Antitumor Sulfonamides Targeting G1 Phase of the Cell Cycle

2. Novel Terphenyls as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents

3. Pyrazolopyrimidine-2,4-dione Sulfonamides: Novel and Selective Calcitonin Inducers