Development of cationic peptide-based hydrogels loaded with iopamidol for CEST-MRI detection-Reference-Cited by-同舟云学术

Development of cationic peptide-based hydrogels loaded with iopamidol for CEST-MRI detection

Published:2023 Issue:31 Volume:11 Page:7435-7441
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Di Gregorio Enza¹^ORCID,Rosa Elisabetta²,Ferrauto Giuseppe¹^ORCID,Diaferia Carlo²,Gallo Enrico³,Accardo Antonella²^ORCID,Terreno Enzo¹^ORCID

Affiliation:

1. Molecular and Preclinical Imaging Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, Turin, Italy

2. Department of Pharmacy and Interuniversity Research Centre on Bioactive Peptides (CIRPeB) “Carlo Pedone”, University of Naples “Federico II”, Via D. Montesano 49, Naples 80131, Italy

3. IRCCS Synlab SDN, Via Gianturco 113, Naples, 80143, Italy

Abstract

Cationic hexapeptide Ac-K1 hydrogels were loaded with iopamidol, an X-ray and CEST-MRI contrast agent. These soft, injectable and non-toxic systems are promising candidates for the development of smart MRI detectable bioscaffolds.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00187C

Reference28 articles.

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3. In Vitro and In Vivo Assessment of Nonionic Iodinated Radiographic Molecules as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Tumor Perfusion Agents

4. Iopamidol: Exploring the potential use of a well-established x-ray contrast agent for MRI

5. A comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH

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