Platinum nanoparticles labelled with iodine-125 for combined “chemo-Auger electron” therapy of hepatocellular carcinoma

Author:

Wawrowicz Kamil1ORCID,Żelechowska-Matysiak Kinga1ORCID,Majkowska-Pilip Agnieszka12ORCID,Wierzbicki Mateusz3ORCID,Bilewicz Aleksander1ORCID

Affiliation:

1. Centre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16 St., 03-195 Warsaw, Poland

2. Department of Nuclear Medicine, Central Clinical Hospital of the Ministry of the Interior and Administration, Wołoska 137 St., 02-507 Warsaw, Poland

3. Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, Ciszewskiego 8 St., 02-786 Warsaw, Poland

Abstract

Here we present for the first time iodine-125 labeled platinum nanoparticles targeting the tumor microenvironment for combined “chemo-Auger electron” therapy of hepatocellular carcinoma.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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