Stable π-radical nanoparticles as versatile photosensitizers for effective hypoxia-overcoming photodynamic therapy-Reference-Cited by-同舟云学术

Stable π-radical nanoparticles as versatile photosensitizers for effective hypoxia-overcoming photodynamic therapy

Published:2021 Issue:2 Volume:8 Page:571-576
ISSN:2051-6347
Container-title:Materials Horizons
language:en
Short-container-title:Mater. Horiz.

Author:

Cui Xiao¹²³⁴,Lu Guihong⁵⁶⁷⁸⁴,Dong Shengzhi⁹¹⁰¹¹⁴,Li Shengliang¹²³⁴^ORCID,Xiao Yafang¹²³⁴^ORCID,Zhang Jinfeng⁵⁶⁷⁸⁴^ORCID,Liu Yanhong¹²¹³⁴,Meng Xiangmin¹²¹³⁴^ORCID,Li Feng⁹¹⁰¹¹⁴^ORCID,Lee Chun-Sing¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry Institution Center of Super-Diamond and Advanced Films (COSDAF)

2. City University of Hong Kong

3. Kowloon

4. P. R. China

5. Key Laboratory of Molecular Medicine and Biotherapy

6. School of Life Sciences

7. Beijing Institute of Technology

8. Beijing 100081

9. State Key Laboratory of Supramolecular Structure and Materials

10. College of Chemistry Jilin University Qianjin Avenue 2699

11. Changchun 130012

12. Technical Institute of Physics and Chemistry Chinese Academy of Sciences

13. Beijing 100190

Abstract

A stable π-radical is used as a photosensitizer for photodynamic therapy. Under hypoxic conditions, sufficient O₂⁻˙ generation and cytotoxicity were observed addressing the most important hurdle for successful PDT in a tumor microenvironment.

Funder

National Natural Science Foundation of China

City University of Hong Kong

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MH/D0MH01312A

Reference51 articles.

1. Photodynamic therapy and anti-tumour immunity

2. Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy