Synthesis of precursors and macrocycle analogs of aerucyclamides as anti-trypanosomal agents
Author:
Affiliation:
1. Cátedra de Química Farmacéutica
2. (DQO)
3. Facultad de Química
4. Universidad de la República
5. Montevideo
6. Group Redox Biology of Trypanosomes
7. Institut Pasteur de Montevideo
8. Uruguay
9. Departamento de Bioquímica
Abstract
Macrocycle analogs and key fragments of aerucyclamides were obtained and evaluated against Trypanosoma brucei brucei.
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2012/MD/C2MD20218B
Reference29 articles.
1. Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania
2. The Human African Trypanosomiasis Control and Surveillance Programme of the World Health Organization 2000–2009: The Way Forward
3. Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
4. Drug development from marine natural products
5. Discovery of Potent Cell Migration Inhibitors through Total Synthesis: Lessons from Structure−Activity Studies of (+)-Migrastatin
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