Gold(i) phosphine compounds as parasite attenuating agents for malaria vaccine and drug development

Author:

Ssemaganda Aloysious123ORCID,Low Leanne M.123ORCID,Verhoeft Krista R.123,Wambuzi Mathias4567,Kawoozo Barbarah4567,Nabasumba Sharon B.4567,Mpendo Juliet4567,Bagaya Bernard S.45678,Kiwanuka Noah4567,Stanisic Danielle I.123,Berners-Price Susan J.123ORCID,Good Michael F.123

Affiliation:

1. Institute for Glycomics

2. Griffith University

3. Australia

4. UVRI-IAVI HIV Vaccine Program

5. Uganda Virus Research Institute

6. Entebbe

7. Uganda

8. Department of Immunology and Molecular Biology

Abstract

The asexual blood-stagePlasmodiumparasite attenuating properties of gold(i) phosphine compounds are exploited in a novel strategy for malaria vaccine development.

Funder

National Health and Medical Research Council

Griffith University

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

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