Chiral ion-pair organocatalyst promotes highly enantioselective 3-exo iodo-cycloetherification of allyl alcohols

Author:

Shen Zhigao12345,Pan Xixian675,Lai Yisheng89101112,Hu Jiadong89101112,Wan Xiaolong13145,Li Xiaoge13145,Zhang Hui1516175,Xie Weiqing12345

Affiliation:

1. Shaanxi Key Laboratory of Natural Products & Chemical Biology

2. College of Science

3. Northwest A&F University

4. Yangling 712100

5. China

6. Hubei Collaborative Innovation Center for Rare Metal Chemistry

7. Hubei Normal University

8. State Key Laboratory of Natural Medicines

9. Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases

10. Center of Drug Discovery

11. China Pharmaceutical University

12. Nanjing 210009

13. Shanghai Institute of Organic Chemistry

14. Chinese Academy of Sciences

15. School of Science & Laboratory for Microstructures

16. Instrumental Analysis and Research Center

17. Shanghai University

Abstract

Enantioselective 3-exo iodo-cycloetherification of allyl alcohols was realized by employing a novel ion-pair organocatalyst.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference72 articles.

1. F. A. Carey and R. J.Sundberg, Advanced Organic Chemistry, Part B, 5th edn, Plenum, New York, 2007, p. 298

2. R. C. Larock , Comprehensive Organic Transformations, 2nd edn, Wiley-VCH, New York, 1999, p. 638

3. Relative Stereochemistry Determination and Synthesis of the Major Chlorosulfolipid from Ochromonas danica

4. Enantioselective Total Synthesis of (−)-Napyradiomycin A1 via Asymmetric Chlorination of an Isolated Olefin

5. Total synthesis of a chlorosulpholipid cytotoxin associated with seafood poisoning

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