Double-peak signal features in microfluidic impedance flow cytometry enable sensitive measurement of cell membrane capacitance

Author:

Mahesh Karthik1234ORCID,Varma Manoj12345,Sen Prosenjit1234ORCID

Affiliation:

1. Centre for Nano Science and Engineering (CeNSE)

2. Indian Institute of Science (IISc)

3. Bangalore 560012

4. India

5. Robert Bosch Centre for Cyber Physical Systems (RBCCPS)

Abstract

In a microfluidic impedance cytometer with co-planar microelectrodes, frequency-dependent signal features of reactive impedance were found to be highly sensitive to cell membrane capacitance and subsequently used to distinguish cell populations.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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