Microfluidics-based single cell analysis reveals drug-dependent motility changes in trypanosomes-Reference-Cited by-同舟云学术

Microfluidics-based single cell analysis reveals drug-dependent motility changes in trypanosomes

Published:2015 Issue:8 Volume:15 Page:1961-1968
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Hochstetter Axel¹²³⁴,Stellamanns Eric⁵⁶⁷⁸,Deshpande Siddharth¹²³⁴,Uppaluri Sravanti⁵⁶⁷⁸,Engstler Markus⁹¹⁰¹¹¹²⁸,Pfohl Thomas¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. University of Basel

3. 4056 Basel

4. Switzerland

5. Department of Complex Fluids

6. Max Planck Institute for Dynamics and Self-Organization

7. 37073 Göttingen

8. Germany

9. Department of Cell and Developmental Biology

10. Biocentre

11. University of Würzburg

12. 97074 Würzburg

Abstract

Combination of microfluidics with optical tweezers is used in order to analyze the impact of drugs and chemicals on the motility of unicellular parasites.

Funder

Deutsche Forschungsgemeinschaft

Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/LC/C5LC00124B

Reference49 articles.

1. On-chip investigation of cell–drug interactions

2. Microfluidic devices for cellomics: a review

3. Revisiting lab-on-a-chip technology for drug discovery

4. In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds

5. Luminescent multiplex viability assay for Trypanosoma brucei gambiense

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