Synthesis of a SiO2/TiO2 hybrid boronate affinity monolithic column for specific capture of glycoproteins under neutral conditions
Author:
Affiliation:
1. Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education)
2. College of Chemistry and Molecular Sciences
3. Wuhan University
4. Wuhan 430072, P.R. China
5. College of Pharmacy
Abstract
A unique boronate-functionalized SiO2/TiO2 hybrid monolithic column was synthesized by a facile approach. The monolith exhibited specific capacity to capture glycoproteins and antibodies in aqueous solution at neutral pH.
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/AN/C3AN02088F
Reference36 articles.
1. Protein glycosylation
2. Glycosylation and the Immune System
3. Role of Glycosylation in Development
4. Strategies for analysis of glycoprotein glycosylation
5. Glycocapture-based proteomics for secretome analysis
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