Direct C(sp<sup>2</sup>)–H fluoroalkylation of quinoxalin-2(1<i>H</i>)-ones with (fluoroalkyl)triphenylphosphonium salts and alkenes-Reference-Cited by-同舟云学术

Direct C(sp²)–H fluoroalkylation of quinoxalin-2(1H)-ones with (fluoroalkyl)triphenylphosphonium salts and alkenes

Published:2023 Issue:21 Volume:10 Page:5375-5382
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Wenwen¹,Zhu Tonghao¹,Wu Jie¹²³^ORCID

Affiliation:

1. School of Pharmaceutical and Chemical Engineering & Institute for Advanced Studies, Taizhou University, 1139 Shifu Avenue, Taizhou 318000, China

2. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China

3. School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, 453007, China

Abstract

A photoredox-catalyzed direct C(sp2)–H fluoroalkylation of quinoxalin-2(1H)-ones with (fluoroalkyl)triphenylphosphonium salts and alkenes is described, providing a practical approach for the generation of diverse fluoroalkyl-containing quinoxalin-2(1H)-ones.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Henan Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO01247F

Reference52 articles.

1. Advances in the Chemistry of Quinoxalinone Derivatives

2. Chemistry, Biological Properties and SAR Analysis of Quinoxalinones

3. Quinoxalin-2(1H)-One Derivatives As Inhibitors Against Hepatitis C Virus

4. Synthesis of Some New Quinoxalines and 1,2,4-Triazolo[4,3-a]-quinoxalines for Evaluation ofin vitro Antitumor and Antimicrobial Activities

5. Synthesis and antimicrobial activity of certain novel quinoxalines

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