Plasma metabolic profiling after cortical spreading depression in a transgenic mouse model of hemiplegic migraine by capillary electrophoresis – mass spectrometry
Author:
Affiliation:
1. Department of Human Genetics
2. Leiden University Medical Center
3. Leiden
4. The Netherlands
5. Center for Proteomics and Metabolomics
6. Department of Neurology
Abstract
Cortical spreading depression-induced brain metabolic changes have been captured in the plasma of a transgenic migraine mouse model using CE-MS.
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2015/MB/C5MB00049A
Reference58 articles.
1. Migraine — Current Understanding and Treatment
2. Migraine pathophysiology: lessons from mouse models and human genetics
3. Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4
4. The Clinical Spectrum of Familial Hemiplegic Migraine Associated with Mutations in a Neuronal Calcium Channel
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