Isoquercitrin from Apocynum venetum L. produces an anti-obesity effect on obese mice by targeting C-1-tetrahydrofolate synthase, carbonyl reductase, and glutathione S-transferase P and modification of the AMPK/SREBP-1c/FAS/CD36 signaling pathway in mice in vivo-Reference-Cited by-同舟云学术

Isoquercitrin from Apocynum venetum L. produces an anti-obesity effect on obese mice by targeting C-1-tetrahydrofolate synthase, carbonyl reductase, and glutathione S-transferase P and modification of the AMPK/SREBP-1c/FAS/CD36 signaling pathway in mice in vivo

Published:2022 Issue:21 Volume:13 Page:10923-10936
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Manzoor Majid¹^ORCID,Muroi Makoto²^ORCID,Ogawa Naoko²,Kobayashi Hiroki³,Nishimura Haruna³,Chen Danni¹^ORCID,Fasina Opeyemi B.¹^ORCID,Wang Jianyu¹^ORCID,Osada Hiroyuki²^ORCID,Yoshida Minoru³⁴^ORCID,Xiang Lan¹^ORCID,Qi Jianhua¹^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, 866 Yu Hang Tang Road, Hangzhou, P. R. China

2. Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama 351-0198, Japan

3. Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

4. Department of Biotechnology and Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan

Abstract

In the present study, mice with high-fat-diet-induced obesity were used in investigating the anti-obesity effects of an aqueous extract and isoquercitrin from Apocynum venetum L.

Funder

National Key Research and Development Program of China

Japan Society for the Promotion of Science

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO02438A

Reference40 articles.

1. W.H. Organization , Obesity and overweight. Fact Sheet. June 2016, Retrieved from [Jan 2017], 2017