Mechanochemistryvs.solution growth: striking differences in bench stability of a cimetidine salt based on a synthetic method-Reference-Cited by-同舟云学术

Mechanochemistryvs.solution growth: striking differences in bench stability of a cimetidine salt based on a synthetic method

Published:2018 Issue:45 Volume:20 Page:7242-7247
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Ayoub Ghada¹²³⁴,Štrukil Vjekoslav⁵⁶⁷^ORCID,Fábián László⁸⁹¹⁰¹¹^ORCID,Mottillo Cristina¹²³⁴,Bao Huizhi¹²³⁴,Murata Yasujiro¹²¹³¹⁴¹⁵^ORCID,Moores Audrey¹²³⁴^ORCID,Margetić Davor⁵⁶⁷,Eckert-Maksić Mirjana⁵⁶⁷,Friščić Tomislav¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. McGill University

3. Quebec

4. Canada

5. Ruđer Bošković Institute

6. Zagreb

7. Croatia

8. School of Pharmacy

9. University of East Anglia

10. Norwich

11. UK

12. Institute for Chemical Research

13. Kyoto University

14. Kyoto 611-0011

15. Japan

Abstract

A mechanochemically prepared solvated salt of an archetypal blockbuster drug exhibits significantly different bench stability to analogous material made in solution.

Funder

Unity through Knowledge Fund

Natural Sciences and Engineering Research Council of Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CE/C8CE01727A

Reference47 articles.

1. Pharmaceutical cocrystals: along the path to improved medicines

2. Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges