Preparation of novel S-allyl cysteine chitosan based nanoparticles for use in ischemic brain treatment-Reference-Cited by-同舟云学术

Preparation of novel S-allyl cysteine chitosan based nanoparticles for use in ischemic brain treatment

Published:2024 Issue:1 Volume:14 Page:160-180
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Khan Mohd Faiyaz¹,Ahmad Niyaz²³^ORCID,Alkholifi Faisal K.⁴,Ullah Zabih⁵,Khalid Mohammed Saifuddin⁶,Akhtar Sultan⁷^ORCID,Farooqui Sadaf¹,Khan Nazia⁸,Chaudhary Anis Ahmad⁹,Alawam Abdullah S.⁹,Ali Mohamed A. M.⁹¹⁰

Affiliation:

1. Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia

2. Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P. O. Box 1982, Dammam, 31441, Kingdom of Saudi Arabia

3. Department of Pharmaceutical Sciences, Green Research Lab, Riyadh, Saudi Arabia

4. Department of Pharmacology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj, Saudi Arabia

5. Department of Pharmaceutical Sciences, College of Pharmacy and Dentistry, Buraydah Colleges, Alqassim, Saudi Arabia

6. Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia

7. Department of Physics, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, P. O. Box 1982, Dammam 31441, Saudi Arabia

8. Department of Pharmaceutical Sciences, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia

9. Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia

10. Department of Biochemistry, Faculty of Science, Ain Shams University, Abbassia, 11566, Cairo, Egypt

Abstract

Enhancing the brain bioavailability of S-allyl-l-cysteine (SC) by developing novel S-allyl-l-cysteine chitosan nanoparticles and examining the quantity of SC by developing a novel method of ultra-high performance liquid chromatography-tandem mass spectrometry in ischemic rat brain treatment.

Funder

Deanship of Scientific Research, Prince Sattam bin Abdulaziz University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA05933B

Reference48 articles.

1. Rutin-encapsulated chitosan nanoparticles targeted to the brain in the treatment of Cerebral Ischemia

2. Ischemic brain treated with 6-gingerol loaded mucoadhesive nanoemulsion via intranasal delivery and their comparative pharmacokinetic effect in brain

3. A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin, and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke

4. Catechin Hydrate Ameliorates Redox Imbalance and Limits Inflammatory Response in Focal Cerebral Ischemia

5. S-allyl cysteine mitigates oxidative damage and improves neurologic deficit in a rat model of focal cerebral ischemia