Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport-Reference-Cited by-同舟云学术

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Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport

Published:2019 Issue:7 Volume:10 Page:1976-1985
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Spooner Michael J.¹²³⁴,Li Hongyu⁵⁶⁷⁴^ORCID,Marques Igor⁸⁹¹⁰¹¹¹²^ORCID,Costa Pedro M. R.⁸⁹¹⁰¹¹¹²^ORCID,Wu Xin¹³¹⁴¹⁵^ORCID,Howe Ethan N. W.¹³¹⁴¹⁵^ORCID,Busschaert Nathalie¹²³⁴^ORCID,Moore Stephen J.¹²³⁴,Light Mark E.¹²³⁴,Sheppard David N.⁵⁶⁷⁴^ORCID,Félix Vítor⁸⁹¹⁰¹¹¹²^ORCID,Gale Philip A.¹²³⁴¹³^ORCID

Affiliation:

1. Chemistry

2. University of Southampton

3. Southampton SO17 1BJ

4. UK

5. School of Physiology, Pharmacology and Neuroscience

6. University of Bristol

7. Bristol BS8 1TD

8. Department of Chemistry

9. CICECO – Aveiro Institute of Materials

10. University of Aveiro

11. Aveiro

12. Portugal

13. School of Chemistry

14. The University of Sydney

15. Australia

Abstract

A series of fluorinated tripodal tris-thioureas function as highly active anion transporters across lipid bilayers and cell membranes.

Funder

Engineering and Physical Sciences Research Council

Fundação para a Ciência e a Tecnologia

Australian Research Council

Centro de Investigação em Materiais Cerâmicos e Compósitos

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC05155K

Reference37 articles.

1. Anion transport and supramolecular medicinal chemistry

2. Small-Molecule Lipid-Bilayer Anion Transporters for Biological Applications

3. Development of synthetic membrane transporters for anions

4. Applications of Supramolecular Anion Recognition

5. Structure-Activity Relationships in Cholapod Anion Carriers: Enhanced Transmembrane Chloride Transport through Substituent Tuning

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