Annexin-V/quantum dot probes for multimodal apoptosis monitoring in living cells: improving bioanalysis using electrochemistry-Reference-Cited by-同舟云学术

Annexin-V/quantum dot probes for multimodal apoptosis monitoring in living cells: improving bioanalysis using electrochemistry

Published:2015 Issue:9 Volume:7 Page:4097-4104
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Montón Helena¹²³⁴⁵,Parolo Claudio⁵⁶⁴,Aranda-Ramos Antonio¹²³⁴,Merkoçi Arben⁵⁶⁴⁷⁸,Nogués Carme¹²³⁴

Affiliation:

1. Departament de Biologia Cel·lular

2. Fisiologia i Immunologia

3. Universitat Autònoma de Barcelona

4. 08193 Bellaterra, Spain

5. Nanobioelectronics & Biosensors Group

6. Institut Català de Nanociència i Nanotecnologia ICN2

7. ICREA - Institució Catalana de Recerca i Estudis Avançats

8. 08010 Barcelona, Spain

Abstract

A novel-electrochemical Annexin-V–QD conjugate, which can be also used as a classical-optical label, is applied for apoptosis detection in THP-1 cell cultures. The electrochemical detection of AnnV–QD labeled cells gives qualitative and quantitative results in a fast and cost-effective way.

Funder

Agència de Gestió d'Ajuts Universitaris i de Recerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NR/C4NR07191C

Reference40 articles.

1. Controlled Apoptosis by a Thermally Toggled Nanoscale Amplifier of Cellular Uptake

2. Apoptosis in neurodegenerative disorders

3. Morphological aspects of apoptosis in heart diseases

4. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

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