Isocoumarin formation by heterologous gene expression and modification by host enzymes
Author:
Affiliation:
1. Institut für Pharmazeutische Biologie und Biotechnologie
2. Philipps-Universität Marburg
3. 35037 Marburg
4. Germany
5. State Key Laboratory of Mycology
6. Institute of Microbiology
7. Chinese Academy of Sciences
8. Beijing 100101
9. China
Abstract
The polyketide synthase product was converted to its methylated and hydroxylated derivatives by host endogenous enzymes.
Funder
Deutsche Forschungsgemeinschaft
National Natural Science Foundation of China
China Scholarship Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00989J
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1. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
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4. Iterative polyketide biosynthesis by modular polyketide synthases in bacteria
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