Synthetic and biochemical studies on the effect of persulfidation on disulfide dimer models of amyloid β42 at position 35 in Alzheimer's etiology-Reference-Cited by-同舟云学术

Synthetic and biochemical studies on the effect of persulfidation on disulfide dimer models of amyloid β42 at position 35 in Alzheimer's etiology

Published:2020 Issue:33 Volume:10 Page:19506-19512
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Murakami Kazuma¹²³⁴⁵^ORCID,Kato Haruka¹²³⁴⁵,Hanaki Mizuho¹²³⁴⁵,Monobe Yoko⁶⁷⁵,Akagi Ken-ichi⁶⁷⁵,Kawase Taiji⁸⁹⁵,Hirose Kenji⁸⁹⁵,Irie Kazuhiro¹²³⁴⁵^ORCID

Affiliation:

1. Division of Food Science and Biotechnology

2. Graduate School of Agriculture

3. Kyoto University

4. Kyoto 606-8502

5. Japan

6. National Institute of Biomedical Innovation, Health and Nutrition

7. Osaka 567-0085

8. Nihon Waters, K. K.

9. Tokyo 140-0001

Abstract

Our data do not support the Aβ42 persulfidation hypothesis in Alzheimer's etiology because the neurotoxicity of the homoCys-disulfide-Aβ42 dimer was very weak.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA03429K

Reference45 articles.

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