A natural multifunction and multiscale hierarchical matrix as a drug-eluting scaffold for biomedical applications-Reference-Cited by-同舟云学术

A natural multifunction and multiscale hierarchical matrix as a drug-eluting scaffold for biomedical applications

Published:2024 Issue: Volume: Page:
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Graziani Gabriela¹^ORCID,Triunfo Carla²,Magnabosco Giulia²^ORCID,Fermani Simona²³,Montroni Devis²^ORCID,Ghezzi Daniele⁴,Cappelletti Martina⁴,Baldini Nicola¹⁵,Falini Giuseppe²^ORCID

Affiliation:

1. Biomedical Science, Technologies, and Nanobiotecnology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

2. Department of Chemistry “Giacomo Ciamician”, University of Bologna, Bologna, Italy

3. Interdepartmental Centre for Industrial Research Health Sciences & Technologies, University of Bologna, 40064 Bologna, Italy

4. Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy

5. University of Bologna, Department of Biomedical and Neuromotor Sciences, Bologna, Italy

Abstract

Sea urchin spines are biogenic single crystals of magnesium calcite that are stiff, strong, damage tolerant and light and have a bicontinuous porous structure. Thanks to these peculiar characteristics they can be used as drug-releasing platforms for spine fusion.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB00482E

Reference39 articles.

1. H.Schultz , Sea Urchins: A Guide to Worldwide Shallow Water Species, 2006

2. A.Miskelly , Sea Urchins of the World: Diversity, Symmetry & Design , Ashley Miskelly , 2009

3. Marine reserves demonstrate top-down control of community structure on temperate reefs

4. High-Mg calcite nanoparticles within a low-Mg calcite matrix: A widespread phenomenon in biomineralization

5. Single crystal structure analysis of sea urchin spine calcites: Systematic investigations of the Ca/Mg distribution as a function of habitat of the sea urchin and the sample location in the spine