Affiliation:
1. Department of Bioengineering, Imperial College London, London, W12 0BZ, UK
Abstract
Strategies for reducing CRS in CAR-T cells capitalize on the specificity between CAR-T cells, cytokines, and their receptors, the role of macrophages in cytokine release, and genetic constructs to ablate CAR-T function reversibly and irreversibly.
Funder
Japan Society for the Promotion of Science
Academy of Medical Sciences
Cancer Research UK
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Cited by
9 articles.
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