PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays-Reference-Cited by-同舟云学术

PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays

Published:2017 Issue:34 Volume:15 Page:7117-7121
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Beauvineau Claire¹²³⁴⁵,Guetta Corinne¹²³⁴⁵,Teulade-Fichou Marie-Paule¹²³⁴⁵,Mahuteau-Betzer Florence¹²³⁴⁵^ORCID

Affiliation:

1. Institut Curie

2. PSL Research University

3. CNRS

4. INSERM

5. UMR9187/U1196

Abstract

PhenDV is a light-up probe for G4-fluorescent intercalator displacement. This potent G4-DNA binder discriminates between medium and high-affinity ligands.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01705G

Reference30 articles.

1. G-quadruplex structures: in vivo evidence and function

2. G4 DNA: at risk in the genome

3. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

4. Telomestatin, a Potent Telomerase Inhibitor That Interacts Quite Specifically with the Human Telomeric Intramolecular G-Quadruplex

5. Interaction of Metal Complexes with G-Quadruplex DNA

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