How mithramycin stereochemistry dictates its structure and DNA binding function-Reference-Cited by-同舟云学术

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How mithramycin stereochemistry dictates its structure and DNA binding function

Published:2019 Issue:5 Volume:10 Page:735-741
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Hou Caixia¹²³⁴⁵,Rohr Jürgen¹²³⁴⁵,Parkin Sean¹⁶⁴⁵,Tsodikov Oleg V.¹²³⁴⁵^ORCID

Affiliation:

1. University of Kentucky

2. Department of Pharmaceutical Sciences

3. College of Pharmacy

4. Lexington

5. USA

6. Department of Chemistry

Abstract

The crystal structures of mithramycin and its analogue reveal how the chemistry of mithramycin shapes it for DNA binding.

Funder

National Institutes of Health

U.S. Department of Defense

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00100J

Reference37 articles.

1. Experiences in the Treatment of Paget's Disease of Bone With Mithramycin

2. Mithramycin Therapy in Testicular Cancer

3. Mithramycin Therapy in Disseminated Germinal Testicular Cancer

4. Mithramycin in the Treatment of Pagetʼs Disease of Bone

5. Long-Term Follow-Up of Stage III Testicular Carcinoma Treated With Mithramycin (Plicamycin)

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4. DNA Minor Groove-Induced cis–trans Isomerization of a Near-Infrared Fluorescent Probe;Biochemistry;2021-06-18

5. Practical hints and tips for solution of pseudo-merohedric twins: three case studies;Acta Crystallographica Section E Crystallographic Communications;2021-04-09

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