Dihydropyrimidine-2-thiones as Eg5 inhibitors and L-type calcium channel blockers: potential antitumour dual agents-Reference-Cited by-同舟云学术

Dihydropyrimidine-2-thiones as Eg5 inhibitors and L-type calcium channel blockers: potential antitumour dual agents

Published:2019 Issue:9 Volume:10 Page:1589-1598
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

González-Hernández Elena¹²³⁴⁵,Aparicio Rubén⁶²³⁴⁵^ORCID,Garayoa Mercedes⁷⁸⁴⁵⁹^ORCID,Montero M. José⁶²³⁴⁵^ORCID,Sevilla M. Ángeles⁶²³⁴⁵^ORCID,Pérez-Melero Concepción¹²³⁴⁵^ORCID

Affiliation:

1. Pharmaceutical Sciences Department

2. School of Pharmacy

3. University of Salamanca

4. 37007 Salamanca

5. Spain

6. Physiology and Pharmacology Department

7. Institute of Biomedical Research of Salamanca (IBSAL)

8. University Hospital of Salamanca

9. Cancer Research Center

Abstract

4-Aryldihydropyrimidine-2-thiones are proposed as potential antitumour dual agents, both as Eg5 inhibitors and L-type calcium channel blockers.

Funder

Ministerio de Economía y Competitividad

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00108E

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