Glycyrrhetinic acid-decorated and reduction-sensitive micelles to enhance the bioavailability and anti-hepatocellular carcinoma efficacy of tanshinone IIA-Reference-Cited by-同舟云学术

Glycyrrhetinic acid-decorated and reduction-sensitive micelles to enhance the bioavailability and anti-hepatocellular carcinoma efficacy of tanshinone IIA

Published:2016 Issue:1 Volume:4 Page:167-182
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Chen Fengqian¹²³⁴⁵,Zhang Jinming¹²³⁴⁵,He Yao⁶⁷⁸⁹¹⁰,Fang Xiefan¹¹¹²¹³¹⁴¹⁵,Wang Yitao¹²³⁴⁵,Chen Meiwan¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicine

2. Institute of Chinese Medical Sciences

3. University of Macau

4. Macao 999078

5. China

6. Pharmacy College

7. State Key Laboratory Breeding Base of Systematic Research

8. Development and Utilization of Chinese Medicine Resources

9. Chengdu University of Traditional Chinese Medicine

10. Chengdu

11. Department of Pediatrics

12. College of Medicine

13. University of Florida

14. Gainesville

15. USA

Abstract

A dual-functional polymeric micellar system with HCC-targeting property mediated by glycyrrhetinic acid and controlled-intracellular drug release by a redox-sensitive approach was developed for synergetic anti-HCC effects.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/BM/C5BM00224A

Reference56 articles.

1. Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma

2. Hepatocellular carcinoma: a global view

3. Polymer Therapeutics: Concepts and Applications

4. Drug targeting to the diseased liver

5. Functionalized Micellar Systems for Cancer Targeted Drug Delivery

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