Metal-free synthesis of difluoro/trifluoromethyl carbinol-containing chromones <i>via</i> tandem cyclization of <i>o</i>-hydroxyaryl enaminones-Reference-Cited by-同舟云学术

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Metal-free synthesis of difluoro/trifluoromethyl carbinol-containing chromones via tandem cyclization of o-hydroxyaryl enaminones

Published:2023 Issue:46 Volume:21 Page:9236-9241
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wu Long-Hui¹,Liu Xia¹,Liu Zhao-Wen¹,Chen Zhi-Xi¹,Fu Xin-Lei¹,Yang Kai¹^ORCID

Affiliation:

1. College of pharmacy, Gannan Medical University, Ganzhou 341000, P. R. China

Abstract

A convenient and efficient method for the synthesis of difluoro/trifluoromethyl carbinol-containing chromone derivatives has been developed.

Funder

Natural Science Foundation of Jiangxi Province

Education Department of Jiangxi Province

Gannan Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01582C

Reference55 articles.

1. Ligand-Less Iron-Catalyzed Aromatic Cross-Coupling Difluoromethylation of Grignard Reagents with Difluoroiodomethane

2. Synthesis of α-Difluoromethyl Aryl Ketones through a Photoredox Difluoromethylation of Enol Silanes

3. Visible-Light-Induced Radical Difluoromethylation/Cyclization of Unactivated Alkenes: Access to CF2H-Substituted Quinazolinones

4. Difluoromethyl Bioisostere: Examining the “Lipophilic Hydrogen Bond Donor” Concept

5. Regioselective Direct C–H Trifluoromethylation of Pyridine

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