One-pot access to 11-methyl-6H-indolo[2,3-b]quinolines via iodine-mediated annulation of indoles with 2-vinylanilines and evaluation of their biological activities-Reference-Cited by-同舟云学术

One-pot access to 11-methyl-6H-indolo[2,3-b]quinolines via iodine-mediated annulation of indoles with 2-vinylanilines and evaluation of their biological activities

Published:2023 Issue:24 Volume:10 Page:6192-6199
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yan Jinglan¹^ORCID,Fang Zeguo¹^ORCID,Su Jianglong¹,He Qun¹,Al-Maharik Nawaf²,Zhang Qian¹,Wei Yanhong¹,Li Dong¹^ORCID

Affiliation:

1. National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), New Materials and Green Manufacturing Talent Introduction and Innovation Demonstration Base, Hubei University of Technology, Wuhan 430068, China

2. Department of Chemistry, Faculty of Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine

Abstract

A simple, straightforward and efficient method for the synthesis of a series of 11-methyl-6H-indolo[2,3-b]quinolines bearing different substituents on the indole and quinoline rings is described.

Funder

Hubei Provincial Department of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO01319G

Reference61 articles.

1. In Vitro and in Vivo Antiplasmodial Activity of Cryptolepine and Related Alkaloids from Cryptolepis sanguinolenta

2. Isolation, Biological Activities and Synthesis of Indoloquinoline Alkaloids: Cryptolepine, Isocryptolepine and Neocryptolepine

3. An efficient iron-promoted synthesis of 6H-indolo[2,3-b]quinolines and neocryptolepine derivatives

4. Synthesis and Structure-Activity Relationship of Methyl-Substituted Indolo[2,3-b]quinolines: Novel Cytotoxic, DNA Topoisomerase II Inhibitors

5. Jusbetonin, the First Indolo[3,2-b]quinoline Alkaloid Glycoside, from Justicia betonica

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