Palladium-catalyzed synthesis of β-hydroxy compounds via a strained 6,4-palladacycle from directed C–H activation of anilines and C–O insertion of epoxides
Author:
Affiliation:
1. School of Chemical Engineering
2. Yeungnam University
3. Gyeongsan 38541
4. Republic of Korea
5. Department of Chemistry
6. Oregon State University
7. Corvallis
8. USA
Abstract
The combined experimental and computational study on palladium-catalyzed regioselective C–H functionalization of O-coordinating directing groups with epoxides is described.
Funder
National Research Foundation of Korea
National Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01462A
Reference49 articles.
1. Nickel‐Catalyzed Stereospecific C−H Coupling of Benzamides with Epoxides
2. Practical Pd(II)-Catalyzed C–H Alkylation with Epoxides: One-Step Syntheses of 3,4-Dihydroisocoumarins
3. Palladium-Catalyzed Oxirane-Opening Reaction with Arenes via C–H Bond Activation
4. Palladium-Catalyzed C(sp2)-H Bond Alkylation of Ketoximes by Using the Ring-Opening of Epoxides
5. PdIV Species Mediation in PdII-Catalyzed Direct Alkylation of Arenes with Oxiranes: A DFT Study
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