The pH dependent mechanisms of non-enzymatic peptide bond cleavage reactions
Author:
Affiliation:
1. School of Chemical & Biomolecular Engineering
2. Georgia Institute of Technology
3. Atlanta
4. USA
5. NSF/NASA Center for Chemical Evolution
6. School of Chemistry & Biochemistry
Abstract
Peptide cleavage can occur through scission and backbiting, depending on the pH.
Funder
National Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2020/CP/C9CP05240B
Reference33 articles.
1. Kinetics of the Hydrolysis of Simple Glycine Peptides
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4. Stepwise degradations and deamidation of the eye lens protein α-crystallin in ageing
5. Pathways for the formation and evolution of peptides in prebiotic environments
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