Aggregation of polyethylene glycol polymers suppresses receptor-mediated endocytosis of PEGylated liposomes-Reference-Cited by-同舟云学术

Aggregation of polyethylene glycol polymers suppresses receptor-mediated endocytosis of PEGylated liposomes

Published:2018 Issue:9 Volume:10 Page:4545-4560
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Shen Zhiqiang¹²³⁴,Ye Huilin¹²³⁴,Kröger Martin⁵⁶⁷⁸⁹^ORCID,Li Ying¹²³⁴^ORCID

Affiliation:

1. Department of Mechanical Engineering and Institute of Materials Science

2. University of Connecticut

3. Storrs

4. USA

5. Department of Materials

6. Polymer Physics

7. ETH Zürich

8. CH-8093 Zurich

9. Switzerland

Abstract

The aggregation of PEG polymers during the membrane wrapping process of PEGylated liposomes can introduce a large free energy barrier, thereby limiting the cellular uptake of PEGylated liposomes.

Funder

University of Connecticut

General Electric

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C7NR09011K

Reference78 articles.

1. Nanocarriers as an emerging platform for cancer therapy

2. Designing materials for biology and medicine

3. The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

4. Analysis of nanoparticle delivery to tumours

5. Therapeutic Nanoparticles for Drug Delivery in Cancer

Cited by 63 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain targeting;2024-09-06

2. Targeted delivery of bee venom to A549 lung cancer cells by PEGylate liposomal formulation: an apoptotic investigation;Scientific Reports;2024-07-27

3. A lava-inspired proteolytic enzyme therapy on cancer with a PEG-based hydrogel enhances tumor distribution and penetration of liposomes;Journal of Nanobiotechnology;2024-05-02

4. Structural and energetic properties of lecithin liposomes encapsulating coenzyme Q10 from coarse-grained simulations;Chemical Papers;2024-04-04

5. Uncovering the Importance of Ligand Mobility on Cellular Uptake of Nanoparticles: Insights from Experimental, Computational, and Theoretical Investigations;ACS Nano;2024-02-12