Rapid access to C2-quaternary 3-methyleneindolines<i>via</i>base-mediated post-Ugi Conia-ene cyclization-Reference-Cited by-同舟云学术

Rapid access to C2-quaternary 3-methyleneindolinesviabase-mediated post-Ugi Conia-ene cyclization

Published:2023 Issue:21 Volume:59 Page:3099-3102
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Zhao Shuang¹,He Yi¹,Gao Feiyu¹,Wei Yue¹,Zhang Jiawei¹,Chen Mengxiao¹,Gao Yunyun¹,Zhang Yuan¹,Liu Jun-Yan¹,Guo Zufeng¹,Li Zhenghua²^ORCID,Nie Shenyou¹^ORCID

Affiliation:

1. Center for Novel Target and Therapeutic Intervention, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China

2. School of Science, Westlake University, Zhejiang 310030, China

Abstract

Highly efficient synthesis of diverse 2,2-disubstituted 3-methyleneindoline derivatives through a one-pot base-promoted post-Ugi 5-exo-dig “Conia-ene”-type cyclization has been disclosed.

Funder

Chongqing Medical University

Science and Technology Planning Project of Yuzhong District of Chongqing City

Natural Science Foundation of Chongqing

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC06281J

Reference39 articles.

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4. Total Synthesis of (+)-Hinckdentine A: Harnessing Noncovalent Interactions for Organocatalytic Bromination

5. Reinventing the wheel for enabling the synthesis of hinckdentine A

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