One-pot peptide cyclisation and surface modification of photosensitiser-loaded red blood cells for targeted photodynamic therapy-Reference-Cited by-同舟云学术

One-pot peptide cyclisation and surface modification of photosensitiser-loaded red blood cells for targeted photodynamic therapy

Published:2021 Issue:23 Volume:9 Page:7832-7837
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Chu Jacky C. H.¹^ORCID,Shao Chihao²,Ha Summer Y. Y.¹^ORCID,Fong Wing-Ping³^ORCID,Wong Clarence T. T.²^ORCID,Ng Dennis K. P.¹^ORCID

Affiliation:

1. Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China

2. Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China

3. School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China

Abstract

We report herein a one-pot approach to cyclise a tumour-targeting RGD peptide and conjugate it on the surface of red blood cells loaded with photosensitisers. Such design allows selective binding against target cells, leading to enhanced PDT effect.

Funder

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM01306H

Reference36 articles.

1. Deciphering cell–cell interactions and communication from gene expression

2. Engineering the Surface of Therapeutic “Living” Cells

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