Deuteration of terminal alkynes realizes simultaneous live cell Raman imaging of similar alkyne-tagged biomolecules

Author:

Egoshi Syusuke1ORCID,Dodo Kosuke12ORCID,Ohgane Kenji1ORCID,Sodeoka Mikiko12ORCID

Affiliation:

1. Synthetic Organic Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

2. RIKEN Center for Sustainable Resource Science, 2-1, Hirosawa, Wako, Saitama 351-0198, Japan

Abstract

Two-color Raman imaging of D-alkynes and H-alkynes makes it possible to distinguish and observe similar small molecules in live cells.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Corporation

RIKEN

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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