A low background D–A–D type fluorescent probe for imaging of biothiols in living cells

Author:

Chen Dugang12345ORCID,Yang Juliang67895,Dai Jun1011121314,Lou Xiaoding67895,Zhong Cheng1516175,Yu Xianglin12345,Xia Fan67895ORCID

Affiliation:

1. Key Laboratory for Green Chemical Process of Ministry of Education

2. School of Chemical Engineering and Pharmacy

3. Wuhan Institute of Technology

4. Wuhan 430205

5. P. R. China

6. Engineering Research Center of Nano-Geomaterials of Ministry of Education

7. Faculty of Materials Science and Chemistry

8. China University of Geosciences

9. Wuhan 430074

10. Department of Obstetrics and Gynecology

11. Tongji Hospital

12. Tongji Medical College

13. Huazhong University of Science and Technology

14. Wuhan 430030

15. College of Chemistry and Molecular Science

16. Wuhan University

17. Wuhan 430072

Abstract

The design strategy of a bioprobe based on a D–A–D type fluorophore was discussed, and CBFB constructed by this kind of fluorophore showed specific biothiol recognition in living cells.

Funder

National Natural Science Foundation of China

Wuhan Institute of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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