A comparative study on the synthesis and crystal structures of Ni(ii) complexes bearing tetradentate N2O2 donor Schiff bases: biomolecular interactions, cytotoxicities and molecular docking

Author:

İnci Özbağcı Duygu1ORCID,İlkar Erdağı Sevinç2ORCID,Aydın İpek3,Aydın Rahmiye1,Zorlu Yunus4ORCID,Arı Ferda3

Affiliation:

1. Department of Chemistry, Faculty of Arts and Sciences, Bursa Uludag University, 16059 Bursa, Turkey

2. Department of Chemistry, Faculty of Arts and Sciences, Kocaeli University, Umuttepe Campus, 41380 Kocaeli, Turkey

3. Department of Biology, Faculty of Arts and Sciences, Bursa Uludag University, 16059 Bursa, Turkey

4. Department of Chemistry, Faculty of Science, Gebze Technical University, Gebze, Kocaeli, 41400, Turkey

Abstract

As potential drug candidates N2O2-type tetradentate Schiff bases and their Ni(ii) complexes have been synthesized and investigated in vitro biomolecular (CT-DNA/BSA) interactions and biological activities.

Funder

Bursa Uludağ Üniversitesi

Publisher

Royal Society of Chemistry (RSC)

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